About this work
In 2009, the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium was formed to facilitate genome-wide association study meta-analyses among longitudinal cohort studies. Our collaborative group, the Fatty acids & Outcomes Research Consortium (FORCE), has been formed within the conceptual framework of CHARGE to understand the relationships between fatty acids from the diet and metabolic processes, measured using biomarkers, on chronic disease outcomes . We invite all longitudinal studies with fatty acid biomarker data and ascertained events to participate.
After joining our consortium: Any investigator from participating studies can propose and lead specific projects/manuscripts Investigators can choose to collaborate or not collaborate on specific projects/manuscripts Raw data from each study will not be centrally collected. Instead, each study will perform its own analysis using a standardized analysis plan and results from participating studies will be pooled for meta-analysis Investigators can provide feedback and suggestions on specific papers/analyses conducted within the pooling project group through regular conference calls (bi-monthly) All collaborating studies agree to abide by the principles set forth by the CHARGE consortium, including: transparency, collaboration, timely communication, effective coordination, and sharing of responsibilities, challenges, and opportunities among cohort members. The larger sample sizes of pooled analyses w…
